Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce is a delightful dish that brings together creamy, cheesy flavors with a spicy kick. Perfect for family dinners or impressing guests at gatherings, this pasta recipe stands out with its rich sauce and tender chicken. You’ll love the blend of spices that elevate the classic comfort food into something extraordinary.
Why You’ll Love This Recipe
- Incredibly Flavorful: The combination of garlic, cheese, and Cajun seasoning makes each bite a burst of flavor.
- Quick Preparation: This recipe is easy to prepare in under 40 minutes, making it an ideal weeknight meal.
- Versatile Dish: Pair it with a fresh salad or garlic bread for a complete meal. Perfect for any occasion!
- Crowd-Pleaser: With its creamy texture and bold flavors, this dish will surely delight everyone at your table.
- Customizable: Feel free to add more veggies or adjust the spice level according to your preference.
Tools and Preparation
To make this delicious Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce, you’ll need some essential kitchen tools that will help streamline your cooking process.
Essential Tools and Equipment
- Large pot
- Skillet
- Mixing bowls
- Whisk
- Tongs
Importance of Each Tool
- Large pot: Ideal for boiling pasta evenly without overcrowding, ensuring perfect al dente texture.
- Skillet: Great for searing chicken and creating a rich sauce, allowing for even heat distribution.
- Whisk: Helps incorporate ingredients smoothly into the sauce, preventing clumps.
- Tongs: Useful for flipping chicken during cooking and tossing pasta in the sauce.

Ingredients
For the Chicken
- 2 large boneless, skinless chicken breasts, cut into strips
- 1 cup grated Parmesan cheese, for coating the chicken
For the Pasta
- 12 oz twisted pasta, (gemelli, fusilli, or any twisty shape)
For the Sauce
- 1 tbsp olive oil
- 4 tbsp unsalted butter, divided
- 4 cloves garlic, minced
- 1 tsp Cajun seasoning
- 1 tsp smoked paprika
- Salt and black pepper, to taste
- 1 cup heavy cream
- 1 cup low-sodium chicken broth
- 1 cup shredded mozzarella
- 1 cup shredded cheddar
- 1/2 cup grated Parmesan, for sauce
- 2 oz cream cheese, softened
- 1 tsp Italian seasoning
- 1 tsp dried basil
- 1 tsp crushed red pepper flakes, optional
- Fresh parsley or dried herbs, for garnish
How to Make Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce
Step 1: Boil the Pasta
Begin by boiling a large pot of salted water. Once boiling, add your twisted pasta and cook until al dente. Drain the pasta and set it aside.
Step 2: Prepare the Chicken
While the pasta cooks:
1. Season chicken strips with Cajun seasoning, smoked paprika, salt, and pepper.
2. Press grated Parmesan into the chicken to create a light crust.
Step 3: Cook the Chicken
Heat olive oil and 2 tablespoons of butter in a large skillet over medium-high heat:
– Add the chicken strips to the skillet.
– Sear for about 5–7 minutes until cooked through and golden on both sides.
– During the last minute of cooking, add 1 tablespoon of butter and half of the minced garlic. Let it sizzle for extra flavor before removing from heat.
Step 4: Make the Sauce
In the same skillet:
1. Melt the remaining tablespoon of butter.
2. Add in remaining garlic and sauté for about 30 seconds until fragrant.
3. Pour in heavy cream and chicken broth; stir to combine and bring to a simmer.
Step 5: Incorporate Cheeses
Add softened cream cheese into the pan:
– Whisk until smooth.
– Gradually stir in mozzarella, cheddar, and remaining Parmesan cheese until melted and creamy.
Step 6: Season Your Sauce
Season your sauce with Italian seasoning, dried basil, crushed red pepper flakes (if using), salt, and pepper. Taste and adjust as needed.
Step 7: Combine Pasta with Sauce
Add your twisted pasta into the sauce:
– Toss until well coated.
– Simmer on low heat for about 12 minutes so flavors meld together beautifully.
Step 8: Serve It Up
Plate your cheesy pasta generously:
– Top with garlic Parmesan chicken strips.
– Garnish with fresh parsley or herbs before serving.
Enjoy your flavorful Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce!
How to Serve Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce
Serving Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce is all about presentation and flavor enhancement. Here are some creative ways to serve this delicious dish that will impress your guests and elevate your dining experience.
Garnish with Fresh Herbs
- Use fresh parsley or basil to sprinkle on top for a burst of color and freshness.
Pair with a Side Salad
- A crisp green salad with a light vinaigrette complements the richness of the pasta beautifully.
Add Extra Cheese
- Consider serving extra grated Parmesan or mozzarella on the side for cheese lovers to add more creaminess.
Serve with Crusty Bread
- Provide slices of crusty bread or garlic bread for dipping into the spicy three-cheese sauce.
Offer Red Pepper Flakes
- Set out crushed red pepper flakes for those who enjoy a little more heat in their meal.
Present in Individual Bowls
- Serve each portion in individual bowls for a more elegant presentation, making it perfect for dinner parties.
How to Perfect Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce
Perfecting this dish involves attention to detail and a few simple tips. Here are some suggestions to ensure your Garlic Parmesan Chicken Twisted Pasta turns out amazing every time.
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Use Quality Ingredients: Fresh, high-quality chicken and cheese will greatly enhance the flavor.
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Don’t Overcook the Pasta: Cook the twisted pasta al dente to maintain its texture and allow it to soak up the sauce beautifully.
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Adjust Spice Levels: Tailor the Cajun seasoning according to your preference for spice; start with less if unsure.
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Whisk Thoroughly: When adding cheeses to the sauce, whisk well to achieve a smooth, creamy consistency without lumps.
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Let It Simmer: Allowing the pasta to simmer in the sauce helps it absorb flavors, making each bite delicious.
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Taste as You Go: Adjust seasoning at different stages of cooking based on your personal taste preferences.
Best Side Dishes for Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce
Complementing your Garlic Parmesan Chicken Twisted Pasta with delightful side dishes can enhance your meal. Here are some excellent options:
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Garlic Bread: A classic choice that’s perfect for dipping into creamy sauce—made simply by spreading garlic butter on toasted bread.
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Caesar Salad: Crisp romaine lettuce topped with Caesar dressing, croutons, and grated cheese adds crunch and freshness.
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Roasted Vegetables: Seasonal veggies like zucchini, bell peppers, and asparagus roasted until tender provide a healthy side.
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Coleslaw: A tangy coleslaw offers a refreshing contrast to the rich flavors of the pasta dish.
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Steamed Broccoli: Lightly steamed broccoli retains its vibrant color and adds nutrition without overpowering the main dish.
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Caprese Salad: Slices of fresh mozzarella, tomatoes, and basil drizzled with balsamic glaze create a fresh and tasty accompaniment.
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Antipasto Platter: An assortment of marinated olives, artichokes, and roasted peppers provides a variety of flavors that complement pasta well.
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Sweet Potato Fries: Baked sweet potato fries add sweetness and crunch, balancing the savory notes of the main dish perfectly.
Common Mistakes to Avoid
When preparing Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce, it’s easy to make a few common errors that can affect the final dish. Here are some mistakes to watch out for:
- Overcooking the pasta: Cooking the twisted pasta too long can lead to a mushy texture. Always check for al dente since it will continue cooking in the sauce.
- Not seasoning the chicken properly: Failing to season your chicken strips adequately can result in bland flavors. Be generous with the Cajun seasoning and other spices for a tasty crust.
- Skipping the garlic butter step: This crucial step adds depth and flavor. Don’t rush it; ensure you sauté the garlic just until fragrant to avoid bitterness.
- Adding cheese too quickly: If you add cheese to your sauce too fast, it may clump instead of melt smoothly. Gradually stir in cheese at lower heat for a velvety texture.
- Neglecting to adjust seasoning: After making your sauce, always taste and adjust with salt, pepper, or more spices if needed. This ensures balanced flavors.
- Rushing the simmering time: Allowing the pasta to simmer in the sauce lets it absorb all those delicious flavors. Don’t skip this step for maximum taste.

Storage & Reheating Instructions
Refrigerator Storage
- Store leftovers in an airtight container.
- The Garlic Parmesan Chicken Twisted Pasta can be kept in the fridge for up to 3 days.
Freezing Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce
- Freeze portions in freezer-safe containers or bags.
- It can last up to 2 months in the freezer.
Reheating Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce
- Oven: Preheat oven to 350°F (175°C). Place pasta in an oven-safe dish, cover with foil, and heat for about 20 minutes until warmed through.
- Microwave: Place a serving on a microwave-safe plate and cover; heat on medium power for 2-3 minutes, stirring halfway through.
- Stovetop: In a skillet over medium heat, add a splash of chicken broth or cream and reheat while stirring until hot.
Frequently Asked Questions
If you’re curious about this recipe, here are some frequently asked questions regarding Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce.
Can I use different types of pasta?
Yes! While twisted pasta works best, feel free to substitute with any shape you prefer, like penne or rotini.
How spicy is the Garlic Parmesan Chicken Twisted Pasta?
The spice level can be adjusted based on your preference. Start with less Cajun seasoning if you’re sensitive to heat.
Can I make this dish vegetarian?
Absolutely! Substitute chicken with grilled vegetables or tofu, and use vegetable broth instead of chicken broth for a vegetarian version.
What can I serve alongside this dish?
This pasta pairs beautifully with a fresh salad or garlic bread to round out your meal.
How long does it take to prepare this recipe?
From start to finish, you can expect about 30-35 minutes of preparation time.
Final Thoughts
Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce is not only delicious but also versatile! You can customize it by adding your favorite vegetables or adjusting spice levels. Give this recipe a try, and enjoy its creamy richness combined with savory chicken!
Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce
Indulge in the rich and flavorful Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce, a delightful dish that combines creamy cheese with a tantalizing kick. This easy-to-make recipe is perfect for busy weeknights or when you’re looking to impress guests at dinner gatherings. With tender chicken coated in Parmesan and tossed in a velvety sauce of three cheeses, every bite bursts with flavor. Ready in under 40 minutes, this versatile pasta can be paired with a fresh salad or crusty bread, making it an ideal choice for any occasion. Elevate your dining experience with this comforting and satisfying meal that everyone will love.
- Prep Time: 15 minutes
- Cook Time: 25 minutes
- Total Time: 40 minutes
- Yield: Serves 4
- Category: Main
- Method: Stovetop
- Cuisine: American
Ingredients
- 2 large boneless, skinless chicken breasts
- 12 oz twisted pasta (gemelli or fusilli)
- 1 cup grated Parmesan cheese (for coating)
- 4 cloves garlic, minced
- 1 cup heavy cream
- 1 cup low-sodium chicken broth
- 1 cup shredded mozzarella cheese
- 1 cup shredded cheddar cheese
- 1 tbsp olive oil
- 4 tbsp unsalted butter, divided
- 1 tsp Cajun seasoning
- 1 tsp smoked paprika
- Salt and black pepper, to taste
- 1/2 cup grated Parmesan (for sauce)
- 2 oz cream cheese, softened
- 1 tsp Italian seasoning
- 1 tsp dried basil
- 1 tsp crushed red pepper flakes (optional)
- Fresh parsley or dried herbs, for garnish
Instructions
- Boil salted water in a large pot. Cook twisted pasta until al dente; drain and set aside.
- Season chicken strips with Cajun seasoning and press in grated Parmesan for a crust.
- Sear chicken in olive oil and butter over medium-high heat until golden and cooked through.
- In the same skillet, sauté garlic, then add cream and broth; bring to simmer.
- Whisk in softened cream cheese followed by mozzarella, cheddar, and remaining Parmesan until melted.
- Season sauce to taste; add pasta and toss until well coated.
- Serve topped with chicken strips and garnish with herbs.
Nutrition
- Serving Size: 1 plate (approx. 350g)
- Calories: 680
- Sugar: 3g
- Sodium: 850mg
- Fat: 38g
- Saturated Fat: 22g
- Unsaturated Fat: 10g
- Trans Fat: 0g
- Carbohydrates: 54g
- Fiber: 2g
- Protein: 39g
- Cholesterol: 150mg



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